The parasite Toxoplasma gondii infects approximately 60 million Americans with
an incurable chronic infection that presents a serious risk to pregnant women, their
unborn babies, and immunocompromised people. We have identified a parasite factor
called a bromodomain, that is critical for parasite survival during infection but its essential
function is unknown. The goal of this proposal is to understand the function of this factor
in the parasite, to support the development of effective new treatments for vulnerable
people suffering from toxoplasmosis.
