Sterling A. Tomellini

Professor

Analytical Chemistry
Department of Chemistry
University of New Hampshire
Durham, NH 03824-3598 U.S.A.
Phone: 603-862-2519
Fax: 603-862-4278
sterling@cisunix.unh.edu

Education and Achievements

  • B.S., 1979, University of Rhode Island
  • Ph.D., 1985, Rutgers, the State University of New Jersey
  • Visiting Scientist, 1991-92, Laser Biophysics and Spectroscopy Section, Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland

Research Interests

Chemical separations using liquid chromatography and capillary electrophoresis, vibrational spectroscopic investigations, expert systems.

Current Research Interests

Our research interests have been directed primarily in two areas: vibrational spectroscopy and analytical separations. In vibrational spectroscopy our efforts have included developing systems for computer-assisted spectral interpretation. We have also investigated approaches to improving detection of analytes in aqueous solutions with ATR/FTIR. Other studies have concentrated on using vibrational spectroscopy to study the interactions of bioactive molecules with model membrane systems. For example, the interaction of several bile salts under different solution conditions with multilamellar vesicles of dipalmitoylphosphatidylcholine (DPPC) have been investigated using FTIR spectroscopy.

Another research focus in our laboratory has been developing and improving methods for analytical separations. We are exploring approaches to improve the separations provided by capillary electrophoresis and developing novel approaches for detection in HPLC.

Group Members

Tomellini Research Group members

Liz Brady, Kelsey Packard, Professor Tomellini, Jess Henry

Publications

M. Ertan-Lamontagne, K.A. Parthum, W.R. Seitz, S.A. Tomellini, "Evaluation of Chloroparaffin/PVC Phases for ATR/FTIR Analyses", Appl. Spectrosc., 48, 12, 1539 -1544 (1994).

M. Ertan-Lamontagne, S.R. Lowry, W.R. Seitz and S.A. Tomellini, "Polymer-coated, Tapered Cylindrical ATR Elements for Sensitive Detection of Organic Solutes in Water", Appl. Spectrosc., 49, 9, 1170-1173 (1995).

R. Gobel, R.W. Seitz, S.A. Tomellini, R. Krska, R. Kellner, "Infrared Attenuated Total Reflection Spectroscopic Investigations of the Diffusion Behavior of Chlorinated Hydrocarbons into Polymer Membranes", Vib. Spectrosc., 8, 141-149 (1995).

J.G. Clothier, Jr. and S.A. Tomellini, "Chiral Separation of Verapamil and Related Compounds Using MECC With Mixed Micelles of Bile Salt and Polyoxyethylene Ethers", J. Chromatogr. A, 723, 179-187 (1996).

J.G. Clothier, Jr., L.M. Daley and S.A. Tomellini, "Effects of Bile Salt Structure on Chiral Separations with Mixed Micelles of Bile Salts and Polyoxyethylene Ethers Using MECC", J. Chromatogr. B, 683, 37-45 (1996).

M. Yang and S.A. Tomellini, "Indirect fluorescence detection of aliphatic biogenic polyamines and diamines following chromatographic separation", J. Chromatogr. A, 841, 9-18 (1999).

M. Yang and S.A. Tomellini, "A HPLC Detection Scheme for Underivatized Amino Acids Based on Tryptophan Fluorescence Recovery", Anal. Chim. Acta, 409, 45-53 (2000).

M. Yang and S.A. Tomellini, "Non-derivatization approach to high-performance liquid chromatography-fluorescence detection for aminoglycoside antibiotics based on a ligand displacement reaction" , J. Chromatogr. A, 939, 59-67 (2001).

X. Shen, M. Yang, and S.A. Tomellini, "Indirect fluorescence detection of amino sugars with the use of copper complexes of tryptophan and its analogues following high-performance liquid chromatographic separation", J. Chromatogr. A, 1072, 273-277 (2005).

K.S. Woodin, K.J. Heroux, C.A. Boswell, E.H. Wong, G.R. Weisman, W. Niu, S.A. Tomellini, C.J. Anderson, L.N. Zakharov, A,L. Rheingold, "Kinetic inertness and electrochemical behavior of copper(II) tetraazamacrocyclic complexes: Possible implications for in vivo stability", Eur. J. Inorg. Chem. 23, 4829-4833 (2005).

X. Shen, C.A. Boswell, E.H. Wong, G.R. Weisman, C.J. Anderson, S.A. Tomellini, "Investigation of copper-azamacrocyclic complexes by high-performance liquid chromatography", Biomed. Chromatogr. 20, 37-47 (2006)

Xiaoxuan Shen, Min Yang and Sterling A. Tomellini, "Liquid chromatographic analysis of glucosamine in commercial dietary supplements using indirect fluorescence detection", J. Chromatogr. Sci., 45, 70-75 (2007).

X. Shen and Sterling A. Tomellini, "Indirect Photometric and Fluorometric Detection in High-Performance Liquid Chromatography: A Tutorial Reiview", Critical Reviews in Analytical Chemistry, 37:107-126 (2007).